Shannen Doherty, the “Beverly Hills, 90210” star whose life and career were roiled by illness and tabloid stories, has died at 53.

After years with breast cancer, Doherty died Saturday, according to a statement from her publicist, Leslie Sloane.

“The devoted daughter, sister, aunt and friend was surrounded by her loved ones as well as her dog, Bowie. The family asks for their privacy at this time so they can grieve in peace,” Sloane said Sunday. The news was first reported by People magazine.

Her illness was publicly revealed in a lawsuit filed in 2015 against her former business managers, in which she alleged they mismanaged her money and allowed her health insurance to lapse. She later shared intimate details of her treatment following a single mastectomy. In December 2016, she posted a photo of her first day of radiation, calling the treatment “frightening” for her.

In February 2020, Doherty revealed that the cancer had returned and was at Stage 4. She said she came forward because her health conditions could come out in court. The actor had sued insurance giant State Farm after her California home was damaged in a fire in 2018.

“I have no idea how long I’m going to be on the chemo for. ... That’s not something that I can predict, it’s not something my doctors can predict. And it’s scary, it’s like a big wake-up call,” Doherty said on a late June episode of her podcast “Let’s Be Clear,” adding that a recent change in the shape of her cancer cells meant there were new treatment protocols for her to try. “For the first time in a couple months probably, I feel hopeful because there are so many more protocols now, whereas before I was hopeful — but I was still getting prepared.”

A native of Memphis, Tennessee, Doherty moved to Los Angeles with her family at age 7 and, within a few years, became an actor.

“It was completely my decision,” she told The Associated Press in a 1994 interview. “My parents never pushed me into anything. They support me. It really wouldn’t matter if I was a professional soccer player — they’d still be as supportive and loving.”

As a child star, she worked steadily in such TV series as “Little House on the Prairie,” in which she played Jenny Wilder. She detoured as a teenager to the big screen in “Girls Just Want to Have Fun” (1985) and “Heathers.”

In 1990, the doe-eyed, dark-haired actor won her breakout role as Brenda Walsh in producer Aaron Spelling’s hit teenage melodrama set in posh Beverly Hills. She and Jason Priestley’s Brandon, Brenda’s twin brother, were fish-out-of-water Midwesterners.

But Doherty’s fame came with media scrutiny and accounts of outbursts, drinking and impulsiveness — the latter most notably after a very brief marriage to actor George Hamilton’s son, Ashley. Doherty’s second marriage, in 2002, was to Rick Salomon and was annulled within a year. In 2011, Doherty married photographer Kurt Iswarienko. She filed for divorce in April 2023.

She left “Beverly Hills, 90210” at the end of its fourth season in 1994 (the show aired until 2000), reportedly removed by Spelling because of conflicts with her co-stars and chronic lateness.